Nanog Recombinant Protein
Product Specifications
Background
Nanog is a regulatory protein that is associated with undifferentiated pluripotent cells. The expression of Nanog, which is suppressed in all adult tissues, is restricted to embryonic stem cells and to certain pluripotent cancer cells. Decreased expression of Nanog is strongly correlated with cell differentiation. Nanog, most likely, acts as an intracellular regulator, which maintains pluripotency and self renewal via a STAT3 independent pathway. Recombinant human Nanog is a 34.5 kDa protein, which is synthesized as a 304 amino acid polypeptide lacking a signal sequence for secretion.
NCBI Gene ID
79923
Swiss Prot
Q9H9S0
Accession Number
NP_079141.2
Type
Recombinant Proteins
Source
E. coli
Field of Research
Cancer, Homeostasis, Stem Cell, Other
Shipping Conditions
Room Temp
Storage Conditions
The lyophilized Nanog recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted Nanog is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing Nanog recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=40-121
NCBI Official Name
Nanog homeobox
NCBI Organism
Homo sapiens
Other Product Names
Homeobox protein NANOG, Homeobox transcription factor Nanog, hNanog
Species
Human
Protein ID
153945816
Physical Properties
Lyophilized
Available Sizes
Curated Selection
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