Influenza A virus Neuraminidase Recombinant Protein
Product Specifications
Background
Neuraminidase (NA) and hemagglutinin (HA) are major membrane glycoproteins found on the surface of influenza virus. Hemagglutinin binds to the sialic acid-containing receptors on the surface of host cells during initial infection and at the end of an infectious cycle. Neuraminidase, on the other hand, cleaves the HA-sialic acid bondage from the newly formed virions and the host cell receptors during budding. Neuraminidase thus is described as a receptor-destroying enzyme which facilitates virus release and efficient spread of the progeny virus from cell to cell.
Swiss Prot
H8PF47
Accession Number
H8PF47_9INFA, GISAID
Tag
His Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Infectious Disease
Purity
>90% as determined by SDS-PAGE.
Buffer
Supplied as 0.2 μm filtered solution in PBS, pH7.4, 300 mM NaCl with trehalose as protectant.
Shipping Conditions
Dry Ice
Storage Conditions
Protein MUST be stored at -70˚ C or lower upon receipt. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=31-462
Calculated Molecular Weight
The protein has a calculated MW of 53.2 kDa. The protein migrates as 65 kDa when calibrated against pre-stained protein marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Applications Notes
This recombinant protein can be used for WB. For research use only.
Background Reference 01
Manz B., et al., 2012, Submitted to the EMBL/GenBank/DDBJ databases.
Other Product Names
NA, Neuraminidase
Tested Applications
WB
Species
Influenza A
Physical Properties
Liquid
Curated Selection
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