Influenza A virus Neuraminidase Recombinant Protein

Product Specifications

Background

Neuraminidase (NA) and hemagglutinin (HA) are major membrane glycoproteins found on the surface of influenza virus. Hemagglutinin binds to the sialic acid-containing receptors on the surface of host cells during initial infection and at the end of an infectious cycle. Neuraminidase, on the other hand, cleaves the HA-sialic acid bondage from the newly formed virions and the host cell receptors during budding. Neuraminidase thus is described as a receptor-destroying enzyme which facilitates virus release and efficient spread of the progeny virus from cell to cell.

Swiss Prot

H8PF47

Accession Number

H8PF47_9INFA, GISAID

Tag

His Tag

Type

Recombinant Proteins

Source

HEK293 cells

Field of Research

Infectious Disease

Purity

>90% as determined by SDS-PAGE.

Buffer

Supplied as 0.2 μm filtered solution in PBS, pH7.4, 300 mM NaCl with trehalose as protectant.

Shipping Conditions

Dry Ice

Storage Conditions

Protein MUST be stored at -70˚ C or lower upon receipt. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

The protein has a calculated MW of 53.2 kDa. The protein migrates as 65 kDa when calibrated against pre-stained protein marker under reducing (R) condition (SDS-PAGE) due to glycosylation.