RANTES Antibody [5B3-D5]
Product Specifications
Background
RANTES is a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. It binds to CCR1, CCR3, CCR4 and CCR5 and is one of the major HIV suppressive factors produced by CD8+ T cells. Recombinant RANTES protein induces a dose dependent inhibition of different strains of HIV 1, HIV 2, and simian immunodeficiency virus (SIV) . It is T cell and macrophage specific, induced by mitogens, and belongs to the intercrine beta (chemokine CC) family.
NCBI Gene ID
6352
Swiss Prot
P13501
Accession Number
P13501
Host
Mouse
Reactivity
Human
Immunogen
Monoclonal antibody against human RANTES designated as VL-1 was purified from ascites fluid on a Protein A affinity column.
Clonality
Monoclonal
Clone
5B3-D5
Conjugation
Unconjugated
Type
Primary Antibodies, Functional Antibodies
Field of Research
Chemokines & Cytokines
Concentration
Batch dependent
Modification
None
Shipping Conditions
Room Temp
Storage Conditions
RANTES lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20˚ C. Reconstitute in sterile water to a concentration of 0.1 - 1.0 mg/mL. The antibody is stable for at least six weeks at 2-4˚ C when reconstituted.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=XP-5735-M
Fragment
RANTES antibody was derived form BALB/c mice and belongs to the IgG2b isotype.
Symbol
CCL5
NCBI Official Name
Chemokine (C-C motif) ligand 5
NCBI Organism
Homo sapiens
Other Product Names
Regulated upon activation normally T expressed and presumably secreted, CCL5, TCP228, SISd, D17S136E, SCYA5, C-C motif chemokine 5, EoCP, eoCP, RANTES, SIS-delta
Tested Applications
ELISA, WB, Neutralization Assay
Protein ID
6175077
Physical Properties
Lyophilized
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