TNF-a Antibody [2.1_4E10-1H11]
Product Specifications
Background
Tumor Necrosis Factor Alpha (TNF alpha) is a protein secreted by lipopolysaccharide stimulated macrophages, and causes tumor necrosis when injected into tumour bearing mice. TNF alpha is believed to mediate pathogenic shock and tissue injury associated with endotoxemia.
NCBI Gene ID
7124
Swiss Prot
P01375
Accession Number
P01375
Host
Mouse
Reactivity
Human
Immunogen
The monoclonal antibody was produced in BALB/c X ICR F1 mice using recombinant hTNF-alpha as the immunizing antigen.
Clonality
Monoclonal
Clone
2.1_4E10-1H11
Conjugation
Unconjugated
Type
Primary Antibodies, Functional Antibodies
Field of Research
Immunology, Chemokines & Cytokines, Signal Transduction, Growth Factors
Concentration
Batch dependent
Modification
None
Shipping Conditions
Room Temp
Storage Conditions
TNF-α lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20˚ C. Reconstitute in sterile water to a concentration of 0.1 - 1.0 mg/mL. The antibody is stable for at least six weeks at 2-4˚ C when reconstituted.
Symbol
TNF
NCBI Official Name
Tumor necrosis factor
NCBI Organism
Homo sapiens
Other Product Names
Tumor necrosis factor alpha, TNFA, TNFSF2, Tumor necrosis factor, Cachectin, TNF-a
Tested Applications
ELISA, WB, Neutralization Assay
Protein ID
135934
Physical Properties
Lyophilized
Curated Selection
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