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TNF-a Antibody [2.1_4E10-1H11]

Product Specifications

Background

Tumor Necrosis Factor Alpha (TNF alpha) is a protein secreted by lipopolysaccharide stimulated macrophages, and causes tumor necrosis when injected into tumour bearing mice. TNF alpha is believed to mediate pathogenic shock and tissue injury associated with endotoxemia.

NCBI Gene ID

7124

Swiss Prot

P01375

Accession Number

P01375

Host

Mouse

Reactivity

Human

Immunogen

The monoclonal antibody was produced in BALB/c X ICR F1 mice using recombinant hTNF-alpha as the immunizing antigen.

Clonality

Monoclonal

Clone

2.1_4E10-1H11

Conjugation

Unconjugated

Type

Primary Antibodies, Functional Antibodies

Field of Research

Immunology, Chemokines & Cytokines, Signal Transduction, Growth Factors

Concentration

Batch dependent

Modification

None

Shipping Conditions

Room Temp

Storage Conditions

TNF-α lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20˚ C. Reconstitute in sterile water to a concentration of 0.1 - 1.0 mg/mL. The antibody is stable for at least six weeks at 2-4˚ C when reconstituted.

Symbol

TNF

NCBI Official Name

Tumor necrosis factor

NCBI Organism

Homo sapiens

Other Product Names

Tumor necrosis factor alpha, TNFA, TNFSF2, Tumor necrosis factor, Cachectin, TNF-a

Tested Applications

ELISA, WB, Neutralization Assay

Protein ID

135934

Physical Properties

Lyophilized

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