RANTES Antibody
Product Specifications
Background
RANTES is a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. It binds to CCR1, CCR3, CCR4 and CCR5 and is one of the major HIV suppressive factors produced by CD8+ T cells. Recombinant RANTES protein induces a dose dependent inhibition of different strains of HIV 1, HIV 2, and simian immunodeficiency virus (SIV) . It is T cell and macrophage specific, induced by mitogens, and belongs to the intercrine beta (chemokine CC) family.
NCBI Gene ID
81780
Swiss Prot
P50231
Accession Number
P50231
Host
Rabbit
Reactivity
Rat
Immunogen
Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant rat Rantes.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies, Antibody Pairs
Field of Research
Chemokines & Cytokines
Purification
Anti-rat Rantes specific antibody was purified by affinity chromatography employing immobilized rat RANTES matrix.
Concentration
Batch dependent
Modification
None
Shipping Conditions
Room Temp
Storage Conditions
RANTES antibody is stable for at least 2 years from date of receipt at -20˚ C. The reconstituted antibody is stable for at least two weeks at 2-8˚ C. Frozen aliquots are stable for at least 6 months when stored at -20˚ C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=XP-5258
Symbol
Ccl5
NCBI Official Name
Chemokine (C-C motif) ligand 5
NCBI Organism
Rattus norvegicustus norvegicus
Other Product Names
Scya5, Rantes, Scya5, C-C motif chemokine 5, SIS-delta
Tested Applications
ELISA, WB
Protein ID
1711393
Physical Properties
Lyophilized
Curated Selection
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