PF-4 Antibody

Product Specifications

Background

Platelet factor 4 (PF-4) is a 70 amino acid protein that is released from the alpha granules of activated platelets and binds with high affinity to heparin. Its major physiologic role appears to be neutralization of heparin like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, PF-4 probably has a role in inflammation and wound repair.

NCBI Gene ID

5196

Swiss Prot

P02776

Accession Number

P02776

Host

Rabbit

Reactivity

Human

Immunogen

Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant hPF-4 (human Platelet Factor-4) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies, Antibody Pairs

Field of Research

Immunology, Chemokines & Cytokines

Purification

Anti-hPF-4 specific antibody was purified by affinity chromatography employing immobilized hPF-4 matrix.

Concentration

Batch dependent

Modification

None

Shipping Conditions

Room Temp

Storage Conditions

PF-4 antibody is stable for at least 2 years from date of receipt at -20˚ C. The reconstituted antibody is stable for at least two weeks at 2-8˚ C. Frozen aliquots are stable for at least 6 months when stored at -20˚ C. Avoid repeated freeze-thaw cycles.