M-CSF Antibody
Product Specifications
Background
Macrophage CSF, also known as CSF1, is produced by monocytes, fibroblasts and endothelial cells. It stimulates the formation of macrophage colonies, enhances antibody-dependent, cell-mediated cytotoxicity by monocytes and macrophages, and inhibits bone resorption by osetoclasts. Natural human MCSF is a dimeric glycoprotein of 70-90 kD molecular weight, existing in multiple glycosylation forms. It binds to a 165 kD glycoprotein of the receptor tyrosine kinase subclass III, a family that includes the receptors for platelet derived growth factor (PDGF) and stem cell factor (SCF) .
NCBI Gene ID
1435
Swiss Prot
P09603
Accession Number
P09603
Host
Rabbit
Reactivity
Human
Immunogen
Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant hM-CSF (human M-CSF) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies, Functional Antibodies, Antibody Pairs
Field of Research
Growth Factors
Purification
Anti-hM-CSF specific antibody was purified by affinity chromatography employing immobilized hM-CSF matrix.
Concentration
Batch dependent
Modification
None
Shipping Conditions
Room Temp
Storage Conditions
M-CSF antibody is stable for at least 2 years from date of receipt at -20˚ C. The reconstituted antibody is stable for at least two weeks at 2-8˚ C. Frozen aliquots are stable for at least 6 months when stored at -20˚ C. Avoid repeated freeze-thaw cycles.
Symbol
CSF1
NCBI Official Name
Colony stimulating factor 1 (macrophage)
NCBI Organism
Homo sapiens
Other Product Names
MCSF, CSF-1Macrophage colony-stimulating factor 1, Lanimostim, CSF-1
Tested Applications
ELISA, WB, Neutralization Assay
Protein ID
311033367
Physical Properties
Lyophilized
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