M-CSF Antibody

Product Specifications

Background

Macrophage CSF, also known as CSF1, is produced by monocytes, fibroblasts and endothelial cells. It stimulates the formation of macrophage colonies, enhances antibody-dependent, cell-mediated cytotoxicity by monocytes and macrophages, and inhibits bone resorption by osetoclasts. Natural human MCSF is a dimeric glycoprotein of 70-90 kD molecular weight, existing in multiple glycosylation forms. It binds to a 165 kD glycoprotein of the receptor tyrosine kinase subclass III, a family that includes the receptors for platelet derived growth factor (PDGF) and stem cell factor (SCF) .

NCBI Gene ID

1435

Swiss Prot

P09603

Accession Number

P09603

Host

Rabbit

Reactivity

Human

Immunogen

Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant hM-CSF (human M-CSF) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies, Functional Antibodies, Antibody Pairs

Field of Research

Growth Factors

Purification

Anti-hM-CSF specific antibody was purified by affinity chromatography employing immobilized hM-CSF matrix.

Concentration

Batch dependent

Modification

None

Shipping Conditions

Room Temp

Storage Conditions

M-CSF antibody is stable for at least 2 years from date of receipt at -20˚ C. The reconstituted antibody is stable for at least two weeks at 2-8˚ C. Frozen aliquots are stable for at least 6 months when stored at -20˚ C. Avoid repeated freeze-thaw cycles.