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LIGHT Antibody (biotin)

Product Specifications

Background

LIGHT is a type II membrane protein belonging to the TNF family of membrane-anchored ligands. It is expressed in splenocytes, activated PBL, CD8+ tumor infiltrating lymphocytes, granulocytes and monocytes. LIGHT has the ability to activate NFkB, stimulate proliferation of lymphocytes, and induce apoptosis in certain human tumor cells.

NCBI Gene ID

8740

Swiss Prot

O43557

Accession Number

O43557

Host

Rabbit

Reactivity

Human

Immunogen

Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant hLIGHT (human LIGHT) .

Clonality

Polyclonal

Conjugation

Biotin

Type

Primary Antibodies, Antibody Pairs

Field of Research

Infectious Disease, Apoptosis, Chemokines & Cytokines

Purification

Anti-hLIGHT specific antibody was purified by affinity chromatography and then biotinylated.

Concentration

Batch dependent

Modification

None

Shipping Conditions

Room Temp

Storage Conditions

LIGHT antibody is stable for at least 2 years from date of receipt at -20˚ C. The reconstituted antibody is stable for at least two weeks at 2-8˚ C. Frozen aliquots are stable for at least 6 months when stored at -20˚ C. Avoid repeated freeze-thaw cycles.

Symbol

TNFSF14

NCBI Official Name

Tumor necrosis factor (ligand) superfamily, member 14

NCBI Organism

Homo sapiens

Other Product Names

LTg, TR2, CD258, HVEML, LIGHT, UNQ391/PRO726, Tumor necrosis factor ligand superfamily member 14, Herpes virus entry mediator ligand, HVEM-L

Tested Applications

ELISA, WB

Protein ID

313104028

Physical Properties

Lyophilized

Curated Selection

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