LIGHT Antibody

Product Specifications

Background

LIGHT is a type II membrane protein belonging to the TNF family of membrane-anchored ligands. It is expressed in splenocytes, activated PBL, CD8+ tumor infiltrating lymphocytes, granulocytes and monocytes. LIGHT has the ability to activate NFkB, stimulate proliferation of lymphocytes, and induce apoptosis in certain human tumor cells.

NCBI Gene ID

8740

Swiss Prot

O43557

Accession Number

O43557

Host

Rabbit

Reactivity

Human

Immunogen

Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant hLIGHT (human LIGHT) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies, Antibody Pairs

Field of Research

Infectious Disease, Apoptosis, Chemokines & Cytokines

Purification

Anti-hLIGHT specific antibody was purified by affinity chromatography employing immobilized hLIGHT matrix.

Concentration

Batch dependent

Modification

None

Shipping Conditions

Room Temp

Storage Conditions

LIGHT antibody is stable for at least 2 years from date of receipt at -20˚ C. The reconstituted antibody is stable for at least two weeks at 2-8˚ C. Frozen aliquots are stable for at least 6 months when stored at -20˚ C. Avoid repeated freeze-thaw cycles.