Leptin Antibody

Product Specifications

Background

Leptin plays a critical role in the regulation of body weight by inhibiting food intake and stimulating energy expenditure. Defects in Leptin production cause severe hereditary obesity in rodents and humans. In addition to its effects on body weight, leptin has a variety of other functions, including the regulation of hematopoiesis, angiogenesis, wound healing, and the immune and inflammatory response. The Leptin gene is the human homolog of the gene (ob) mutant in the mouse 'obese' phenotype.

NCBI Gene ID

16846

Swiss Prot

P41160

Accession Number

P41160

Host

Rabbit

Reactivity

Mouse

Immunogen

Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant murine Leptin.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies, Antibody Pairs

Field of Research

Signal Transduction, Growth Factors, Obesity, Chemokines & Cytokines

Purification

Anti-murine Leptin specific antibody was purified by affinity chromatography employing immobilized murine Leptin matrix.

Concentration

Batch dependent

Modification

None

Shipping Conditions

Room Temp

Storage Conditions

Leptin antibody is stable for at least 2 years from date of receipt at -20˚ C. The reconstituted antibody is stable for at least two weeks at 2-8˚ C. Frozen aliquots are stable for at least 6 months when stored at -20˚ C. Avoid repeated freeze-thaw cycles.