IL-16 Antibody (biotin)
Product Specifications
Background
IL16 is a proinflammatory cytokine that is chemotactic for CD4+ T lymphocytes, monocytes, and eosinophils. IL16 is synthesized as a precursor molecule (pro IL16) of approximately 68 kDa and 631 amino acid residues lacking a signal peptide. The sequence and structure of IL16 is conserved across species. In addition to inducing chemotaxis, IL16 upregulates the IL2 receptor and upregulates HLADR expression. It also inhibits T cell receptor (TCR) /CD3 dependent activation, and suppresses HIV1 replication in vitro. Sources of IL16 include epithelial cells, mast cells, T lymphocytes (CD4+ and CD8+), macrophages, synovial fibroblasts, and eosinophils.
NCBI Gene ID
3603
Swiss Prot
Q9UME6
Accession Number
Q9UME6
Host
Rabbit
Reactivity
Human
Immunogen
Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant hIL-16 (human Interleukin-16) .
Clonality
Polyclonal
Conjugation
Biotin
Type
Primary Antibodies, Antibody Pairs
Field of Research
Immunology, Chemokines & Cytokines
Purification
Anti-hIL-16 specific antibody was purified by affinity chromatography and then biotinylated.
Concentration
Batch dependent
Modification
None
Shipping Conditions
Room Temp
Storage Conditions
IL-16 antibody is stable for at least 2 years from date of receipt at -20˚ C. The reconstituted antibody is stable for at least two weeks at 2-8˚ C. Frozen aliquots are stable for at least 6 months when stored at -20˚ C. Avoid repeated freeze-thaw cycles.
Symbol
IL16
NCBI Official Name
Interleukin 16
NCBI Organism
Homo sapiens
Other Product Names
LCF, NIL16, PRIL16, prIL-16
Tested Applications
ELISA, WB
Protein ID
74721081
Physical Properties
Lyophilized
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