EMAP-II Antibody

Product Specifications

Background

EMAP II is a cytokine that is specifically induced by apoptosis. The release of this cytokine renders the tumor associated vasculature sensitive to tumor necrosis factor. Its precursor is identical to the p43 subunit, which is associated with the multi tRNA synthetase complex. Therefore, proEMAP II may function in binding RNA as part of the tRNA synthetase complex in normal cells and in stimulating inflammatory responses after proteolytic cleavage in tumor cells. EMAP II inhibits angiogenesis of vascular beds and suppresses the growth of primary and secondary tumors without affecting normal tissues.

NCBI Gene ID

9255

Swiss Prot

Q12904

Accession Number

Q12904

Host

Goat

Reactivity

Human

Immunogen

Produced from sera of goats pre-immunized with highly pure (>98%) recombinant hEMAP-II (human EMAP-II) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies, Antibody Pairs

Field of Research

Signal Transduction, Chemokines & Cytokines

Purification

Anti-hEMAP-II specific antibody was purified by affinity chromatography employing immobilized hEMAP-II matrix.

Concentration

Batch dependent

Modification

None

Shipping Conditions

Room Temp

Storage Conditions

EMAP-II antibody is stable for at least 2 years from date of receipt at -20˚ C. The reconstituted antibody is stable for at least two weeks at 2-8˚ C. Frozen aliquots are stable for at least 6 months when stored at -20˚ C. Avoid repeated freeze-thaw cycles.

Symbol

AIMP1

NCBI Official Name

Aminoacyl tRNA synthetase complex-interacting multifunctional protein 1

NCBI Organism

Homo sapiens

Other Product Names

P43, HLD3, EMAP2, SCYE1, EMAPII, Aminoacyl tRNA synthase complex-interacting multifunctional protein 1, Multisynthase complex auxiliary component p43, EMAP-2