NALP3 Antibody [Nalpy3-b]
Product Specifications
NCBI Gene ID
114548
Swiss Prot
Q96P20
Host
Mouse
Reactivity
Human
Immunogen
NALP3 (monoclonal Nalpy3-b) antibody was raised against recombinant human NALP3.
Clonality
Monoclonal
Clone
Nalpy3-b
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis
Purification
NALP3 (monoclonal Nalpy3-b) antibody was purified from concentrated hybridoma tissue culture supernatant. NALP3 (monoclonal Nalpy3-b) antibody was purified to ≥95% in SDS-PAGE.
Concentration
Batch dependent
Buffer
PBS containing 0.02% sodium azide
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
NALP3 antibody can be stored at 4˚ C, stable for one year.
Fragment
IgG1
Applications Notes
NALP3 antibody can be used to recognize human NALP3. It detects endogenous protein by Immunoprecipitation (1:50) and Western Blot (1:1,000) . This product is for research use only.
NCBI Official Name
NLR family, pyrin domain containing 3
NCBI Organism
Homo sapiens
Background Reference 01
NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder: L. Agostini, et al.; Immunity 20, 319 (2004) .
Background Reference 02
Nods, Nalps and Naip: intracellular regulators of bacterial-induced inflammation: M. Chamaillard, et al.; Cell. Microbiol. 5, 581 (2003) .
Background Reference 03
Cutting edge: CIAS1/cryopyrin/PYPAF1/NALP3/CATERPILLER 1.1 is an inducible inflammatory mediator with NF-kappa B suppressive properties: W. O'Connor, Jr., et al.; J. Immunol. 171, 6329 (2003) .
Background Reference 04
Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases: F. Martinon and J. Tschopp; Cell 117, 561 (2004) .
Tested Applications
WB, IP
Physical Properties
Liquid
Frequently Asked Questions
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