NALP3 Antibody [Nalpy3-b]

Product Specifications

NCBI Gene ID

114548

Swiss Prot

Q96P20

Host

Mouse

Reactivity

Human

Immunogen

NALP3 (monoclonal Nalpy3-b) antibody was raised against recombinant human NALP3.

Clonality

Monoclonal

Clone

Nalpy3-b

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis

Purification

NALP3 (monoclonal Nalpy3-b) antibody was purified from concentrated hybridoma tissue culture supernatant. NALP3 (monoclonal Nalpy3-b) antibody was purified to ≥95% in SDS-PAGE.

Concentration

Batch dependent

Buffer

PBS containing 0.02% sodium azide

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

NALP3 antibody can be stored at 4˚ C, stable for one year.

Fragment

IgG1

Applications Notes

NALP3 antibody can be used to recognize human NALP3. It detects endogenous protein by Immunoprecipitation (1:50) and Western Blot (1:1,000) . This product is for research use only.

NCBI Official Name

NLR family, pyrin domain containing 3

NCBI Organism

Homo sapiens

Background Reference 01

NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder: L. Agostini, et al.; Immunity 20, 319 (2004) .

Background Reference 02

Nods, Nalps and Naip: intracellular regulators of bacterial-induced inflammation: M. Chamaillard, et al.; Cell. Microbiol. 5, 581 (2003) .

Background Reference 03

Cutting edge: CIAS1/cryopyrin/PYPAF1/NALP3/CATERPILLER 1.1 is an inducible inflammatory mediator with NF-kappa B suppressive properties: W. O'Connor, Jr., et al.; J. Immunol. 171, 6329 (2003) .