SARS-CoV-2 Spike P681H Antibody [1G8D11] (Alpha, Mu Variant)

Product Specifications

Background

N501YP681H

NCBI Gene ID

43740568

Swiss Prot

P0DTC2

Accession Number

QHD43416

Host

Mouse

Reactivity

Virus

Immunogen

PM-9373

Clonality

Monoclonal

Clone

1G8D11

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Infectious Disease, COVID-19

Purification

SARS-CoV-2 (COVID-19) Alpha Variant (B.1.1.7, UK) Spike P681H Antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Homology

Predicted reactivity based on immunogen sequence: SARS-CoV Spike proteins: (25%)

Buffer

SARS-CoV-2 (COVID-19) P681H Mutant Specific Spike antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

SARS-CoV-2 (COVID-19) P681H Mutant Specific Spike antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Fragment

IgG2a, Kappa

Specificity

May cross-react with several virus of interest (VOI) variant lineages that contains P681H mutation, including B.11.318, B.1.621, B.1.621.1, P.3. But all of these lineages are rarely present in current pandemic.

Symbol

NCBI Official Name

Surface glycoprotein

NCBI Organism

Severe acute respiratory syndrome coronavirus 2

Background Reference 01

Duchene et al. Virus Evolution 6 (2) : veaa061.

Background Reference 02

Gu et al. Science 369 (6511) :1603-1607

Background Reference 03

Hoffmann et al. Molecular Cell 78 (4) :779-784.e5

Background Reference 04

Davies et al. Science 372 (6538) :eabg3055.

Background Reference 05

Davies et al. Nature. 593 (7858) :270-274.

Background Reference 06

Graham, et al. The Lancet Public Health. 6 (5) : e335-e345.

Background Reference 07

Horby et al. New & Emerging Threats Advisory Group. 2020;91:264-266.

Other Product Names

SARS-CoV-2 (COVID-19) P681H Mutant Specific Spike antibody: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Surface Glycoprotein, Spike protein