GLUL Monoclonal Antibody
Product Specifications
Background
GLUL Monoclonal Antibody: Glutamate ammonia ligase (GLUL) belongs to the glutamine synthetase family and catalyzes the synthesis of glutamine from glutamate and ammonia. Glutamine is a main source of energy and is involved in cell proliferation, inhibition of apoptosis, and cell signaling. GLUL is expressed during early fetal stages, and plays an important role in controlling body pH by removing ammonia from circulation. Recent studies have suggested that elevated levels of GLUL may be an early marker for hepatocellular carcinoma.
NCBI Gene ID
2752
Accession Number
NP_002056
Host
Mouse
Reactivity
Human, Mouse, Rat
Immunogen
Mouse monoclonal GLUL antibody was raised against a 15 amino acid peptide near the amino terminus of human GLUL.
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Homeostasis
Purification
GLUL Monoclonal Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1303 - Human Brain Tissue Lysate
Concentration
1 mg/mL
Buffer
GLUL Monoclonal Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
GLUL Monoclonal antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=PM-7209
Calculated Molecular Weight
Predicted: 41 kDa
Fragment
IgG1
Applications Notes
GLUL antibody can be used for detection of GLUL by Western blot at 0.5 - 1 μ g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ g/mL. For immunofluorescence start at 20 μ g/mL.
Symbol
GLUL
NCBI Official Name
Glutamate-ammonia ligase
NCBI Organism
Homo sapiens
Background Reference 01
Wang Y, Kudoh J, Kubota R, et al. Chromosomal mapping of a family of human glutamine synthetase genes: functional gene (GLUL) on 1q25, pseudogene (GLULP) on 9p13, and three related genes (GLULL1, GLULL2, GLULL3) on 5q33, 11p15, and 11q24.
Background Reference 02
Long J, Lang ZW, Wang HG, et al. Glutamine synthetase as an early marker for hepatocellular carcinoma based on proteomic analysis of resected small hepatocellular carcinomas. Hepatobiliary Pancreat. Dis. Int. 2010; 9:296-305.
Other Product Names
GLUL Monoclonal Antibody: Glutamate ammonia ligase, glutamine synthase, glutamate decarboxylase, GLNS, GS, PIG43, PIG59, cell proliferation-inducing protein 59
Tested Applications
ELISA, WB, IHC-P, IF
Protein ID
19923206
Physical Properties
Liquid
Available Sizes
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