What is the catalog number for Bim Antibody [1C2C8]?

The catalog number for Bim Antibody [1C2C8] is PM-4819.

What sizes are available for Bim Antibody [1C2C8]?

Bim Antibody [1C2C8] is available in the following size(s): 0.02 mg, 0.1 mg.

How many pack sizes does Bim Antibody [1C2C8] come in?

Bim Antibody [1C2C8] is available in 2 different pack sizes.

Is Bim Antibody [1C2C8] in stock?

Bim Antibody [1C2C8] is currently made to order / not held in immediate stock. Contact us for lead time.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

Bim Antibody [1C2C8]

Product Specifications

Background

Bim Monoclonal Antibody: Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. Bim is another BH3 domain containing protein which can induce apoptosis. Bim interacts with diverse members in the pro-survival Bcl-2 sub-family including Bcl-2, Bcl-xL and Bcl-w. The messenger RNA of Bim is ubiquitously expressed in multiple tissues and cell lines.

NCBI Gene ID

10018

Swiss Prot

O43521

Accession Number

NP_619527

Host

Mouse

Reactivity

Human, Mouse

Immunogen

Mouse monoclonal Bim antibody was raised against a recombinant protein corresponding to amino acids 2 to 198 of human Bim.

Clonality

Monoclonal

Clone

1C2C8

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis, Cancer

Purification

Bim Monoclonal Antibody is immunoaffinity chromotography purified IgG.

Positive Control

Cat. No. 95-107 - Bim Recombinant Protein

Concentration

1 mg/mL

Buffer

Bim Monoclonal Antibody is supplied in PBS containing 0.02% sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Bim monoclonal antibody can be stored at -20˚ C, stable for one year.

Fragment

IgG1

Symbol

BCL2L11

Positive Control 2

Cat. No. 17-004 - K-562 Cell Slide

NCBI Official Name

BCL2-like 11 (apoptosis facilitator)

NCBI Organism

Homo sapiens

Background Reference 01

O'Connor L, Strasser A, O'Reilly LA, et al. Bim: a novel member of the Bcl-2 family that promotes apoptosis. EMBO J. 1998; 17:384-395.

Background Reference 02

Hsu SY, Lin P, and Hsueh AJ BOD (Bcl-2-related ovarian death gene) is an ovarian BH3 domain-containing proapoptotic Bcl-2 protein capable of dimerization with diverse antiapoptotic Bcl-2 members. Mol. Endocrinol. 1998; 12:1432-40.