IL-21 Antibody [SB134f]
Product Specifications
Background
Interleukin-21 (IL-21) is a four helical bundle type I cytokine. The mature form of human IL-21 is a 131 amino acid protein. IL-21 is expressed primarily by NKT and CD4+ T cells, particularly the inflammatory Th17 subset, and has pleiotropic effects on both innate and adaptive immune responses. The effects of IL-21 include promotion of antibody production, NK cell differentiation, proliferation and differentiation of cells of monocyte and granulocyte lineages, costimulation of T cells, and augmentation of antitumor activity of CD8+ T cells. Studies have shown that IL-21 is also an autocrine cytokine that potently induces Th17 differentiation and suppresses Foxp3 expression, and serves as a target for treating inflammatory diseases.
NCBI Gene ID
59067
Swiss Prot
Q9HBE4
Accession Number
Q9HBE4
Host
Mouse
Reactivity
Human
Immunogen
E. coli-expressed human IL-21
Clonality
Monoclonal
Clone
[SB134f]
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Chemokines & Cytokines
Concentration
0.5 mg/mL
Buffer
Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store vial at 2-8˚ C
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=99-804
Fragment
IgG2a
Specificity
IL-21
Applications Notes
IL-21 Antibody [SB134f] for use in ELISA assays.
Symbol
IL21
NCBI Official Name
Interleukin 21
NCBI Organism
Homo sapiens
Other Product Names
Interleukin-21, Za11
Tested Applications
ELISA, WB, IHC-P, IHC-Fr, ICC, Flow, IP, EM
Physical Properties
Liquid
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
