Cytokeratin 8 Antibody [SB37b] (FITC)
Product Specifications
Background
Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1-8) . The two keratin types share only 30% sequence homology. Keratins demonstrate tissue- and differentiation-specific expression profiles. Cytokeratin 8 belongs to the type B (basic) subfamily of keratins and exists in combination with keratin 18. It is expressed in all simple type epithelia tissues (e.g., liver, pancreas, kidney, gut epithelial lining) but not in stratified squamous epithelia. Cytokeratin 8 is also present in the majority of adenocarcinomas and ductal carcinomas but is absent in most squamous cell carcinomas.
NCBI Gene ID
3856
Swiss Prot
P05787
Accession Number
P05787
Host
Mouse
Reactivity
Human
Immunogen
Recombinant C-terminal cytokeratin 8
Clonality
Monoclonal
Clone
[SB37b]
Conjugation
FITC
Type
Primary Antibodies
Field of Research
Cancer
Concentration
0.5 mg/mL
Buffer
Supplied in PBS/NaN3
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store vial at 2-8˚ C
Fragment
IgG2a
Specificity
Cytokeratin 8
Applications Notes
Cytokeratin 8 Antibody [SB37b] for use in flow cytometry, immunohistochemistry / immunocytochemistry, and western blotting assays.
Symbol
KRT8
NCBI Official Name
Keratin 8
NCBI Organism
Homo sapiens
Other Product Names
CK 8, keratin 8
Tested Applications
Flow
Physical Properties
Liquid
Curated Selection
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