Bcl-xL Antibody [7B2.5] (PE)
Product Specifications
Background
Bcl-xL is a 29 kDa member of the Bcl-2 family of proteins involved in regulation of programmed cell death, or apoptosis. It is found in both soluble and membrane fractions of cellular lysates. Like Bcl-2, Bcl-xL has been demonstrated to block apoptosis which is induced by a variety of stimuli and, under certain conditions, offers greater protection against apoptosis than Bcl-2. While formation of heterodimers with the apoptosis-enhancing protein, Bax does not block the apoptosis-suppressing property of Bcl-xL, heterodimerization with Bad effectively inhibits the protective function of Bcl-xL.
NCBI Gene ID
598
Swiss Prot
Q07817
Accession Number
Q07817
Host
Mouse
Reactivity
Human, Mouse, Rat, Rhesus Monkey
Immunogen
Recombinant human Bcl-xS
Clonality
Monoclonal
Clone
[7B2.5]
Conjugation
PE
Type
Primary Antibodies
Field of Research
Transcription, Cancer
Concentration
0.1 mg/mL
Buffer
Supplied in PBS/NaN3 and a stabilizing agent
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store vial at 2-8˚ C
Fragment
IgG3
Specificity
Bcl-xL
Applications Notes
Bcl-xL Antibody [7B2.5] for use in flow cytometry assays.
Symbol
BCL2L1
NCBI Official Name
BCL2-like 1
NCBI Organism
Homo sapiens
Other Product Names
Apoptosis regulator Bcl-X, Bcl-2-like 1 protein, BCL2L1
Tested Applications
IHC-P, IHC-Fr, ICC, Flow
Physical Properties
Liquid
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
GTR15109753 1 Vial
Lentiviral mouse Fnbp4 shRNA (UAS) - Lentiviral mouse Fnbp4 shRNA (UAS, RFP) plasmid
Ask
View Details