Bcl-xL Antibody [7B2.5] (Biotin)
Product Specifications
Background
Bcl-xL is a 29 kDa member of the Bcl-2 family of proteins involved in regulation of programmed cell death, or apoptosis. It is found in both soluble and membrane fractions of cellular lysates. Like Bcl-2, Bcl-xL has been demonstrated to block apoptosis which is induced by a variety of stimuli and, under certain conditions, offers greater protection against apoptosis than Bcl-2. While formation of heterodimers with the apoptosis-enhancing protein, Bax does not block the apoptosis-suppressing property of Bcl-xL, heterodimerization with Bad effectively inhibits the protective function of Bcl-xL.
NCBI Gene ID
598
Swiss Prot
Q07817
Accession Number
Q07817
Host
Mouse
Reactivity
Human, Mouse, Rat, Rhesus Monkey
Immunogen
Recombinant human Bcl-xS
Clonality
Monoclonal
Clone
[7B2.5]
Conjugation
Biotin
Type
Primary Antibodies
Field of Research
Transcription, Cancer
Concentration
0.1 mg/mL
Buffer
Supplied in PBS/NaN3
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store vial at 2-8˚ C
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=99-618
Fragment
IgG3
Specificity
Bcl-xL
Applications Notes
Bcl-xL Antibody [7B2.5] for use in flow cytometry, immunohistochemistry / immunocytochemistry, ELISA, western blotting, and immunoprecipitation assays.
Symbol
BCL2L1
NCBI Official Name
BCL2-like 1
NCBI Organism
Homo sapiens
Other Product Names
Apoptosis regulator Bcl-X, Bcl-2-like 1 protein, BCL2L1
Tested Applications
IHC-P, IHC-Fr, ICC, Flow, IP
Physical Properties
Liquid
Curated Selection
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