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Bcl-xL Antibody [7B2.5] (Biotin)

Product Specifications

Background

Bcl-xL is a 29 kDa member of the Bcl-2 family of proteins involved in regulation of programmed cell death, or apoptosis. It is found in both soluble and membrane fractions of cellular lysates. Like Bcl-2, Bcl-xL has been demonstrated to block apoptosis which is induced by a variety of stimuli and, under certain conditions, offers greater protection against apoptosis than Bcl-2. While formation of heterodimers with the apoptosis-enhancing protein, Bax does not block the apoptosis-suppressing property of Bcl-xL, heterodimerization with Bad effectively inhibits the protective function of Bcl-xL.

NCBI Gene ID

598

Swiss Prot

Q07817

Accession Number

Q07817

Host

Mouse

Reactivity

Human, Mouse, Rat, Rhesus Monkey

Immunogen

Recombinant human Bcl-xS

Clonality

Monoclonal

Clone

[7B2.5]

Conjugation

Biotin

Type

Primary Antibodies

Field of Research

Transcription, Cancer

Concentration

0.1 mg/mL

Buffer

Supplied in PBS/NaN3

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store vial at 2-8˚ C

Fragment

IgG3

Specificity

Bcl-xL

Applications Notes

Bcl-xL Antibody [7B2.5] for use in flow cytometry, immunohistochemistry / immunocytochemistry, ELISA, western blotting, and immunoprecipitation assays.

Symbol

BCL2L1

NCBI Official Name

BCL2-like 1

NCBI Organism

Homo sapiens

Other Product Names

Apoptosis regulator Bcl-X, Bcl-2-like 1 protein, BCL2L1

Tested Applications

IHC-P, IHC-Fr, ICC, Flow, IP

Physical Properties

Liquid

Frequently Asked Questions

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