CD158e1 Antibody [DX9]
Product Specifications
Background
CD158e1 is a 70 kDa transmembrane glycoprotein and a killer cell immunoglobulin (Ig) -like receptor (KIR) that is expressed on a subset of natural killer cells and T cells. The monoclonal antibody DX9 is expressed on a subset of CD3-, CD56+ NK cells isolated from peripheral blood at varying levels (<0.1% to 61%) among individuals but not on thymocytes, B lymphocytes, granulocytes, or monocytes. Interactions with CD158e1 and certain MHC HLA-B antigens on a target cell inhibits cytotoxicity, possibly preventing target cell lysis and death. KIR and MHC class I interactions may regulate NK and T cell response to antigen stimulation.
NCBI Gene ID
3811
Swiss Prot
P43629
Accession Number
P43629
Host
Mouse
Reactivity
Human, Baboon
Immunogen
Human NK clone VL186-1 (CD3-, CD16+, CD56+)
Clonality
Monoclonal
Clone
[DX9]
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Concentration
0.1 mg/mL
Buffer
Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store vial at 2-8˚ C
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=99-608
Fragment
IgG1
Specificity
CD158e1
Applications Notes
CD158e1 Antibody [DX9] for use in flow cytometry, immunohistochemistry / immunocytochemistry, immunoprecipitation, and blocking assays.
Symbol
KIR3DL1
NCBI Official Name
Killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1
NCBI Organism
Homo sapiens
Other Product Names
NKB1, p70, KIR, 3DL1, KIR3DL1, KIR3D, NKAT3
Tested Applications
Flow
Physical Properties
Liquid
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