CD51 Antibody [13C2] (PE)
Product Specifications
Background
CD51 represents the integrin alphaV chain that associates with integrin beta3 (CD61) to form the CD51/CD61 vitronectin receptor on endothelial cells, certain activated leukocytes, NK cells, macrophages, neutrophils, and platelets. CD51 is the most promiscuous integrin alpha subunit as it can form heterodimers with the beta1 (CD29), beta3 (CD61), beta5, beta6 and beta8 subunits in various tissues. CD51/CD61 acts as an activation-independent receptor for platelet attachment and spreading on vitronectin and other RGD-containing proteins including matrix components. It also mediates leukocyte-endothelial cell adhesion via interaction with CD31.
NCBI Gene ID
3685
Swiss Prot
P06756
Accession Number
P06756
Host
Mouse
Reactivity
Human, African Green Monkey, Rabbit, Bovine
Immunogen
Cell suspension containing osteoclasts from osteoclastomas
Clonality
Monoclonal
Clone
[13C2]
Conjugation
PE
Type
Primary Antibodies
Field of Research
Other
Concentration
Batch dependent
Buffer
Supplied in PBS/NaN3 and a stabilizing agent
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store vial at 2-8˚ C
Fragment
IgG1
Specificity
CD51
Applications Notes
CD51 Antibody [13C2] for use in flow cytometry assays.
Symbol
ITGAV
NCBI Official Name
Integrin, alpha V
NCBI Organism
Homo sapiens
Other Product Names
Integrin alphaV, vitronectin receptor, VNR-alpha chain
Tested Applications
Flow
Physical Properties
Liquid
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