CD43 Antibody [DF-T1] (Biotin)
Product Specifications
Background
CD43, a member of the sialomucin family of cell surface receptors, is a 95-135 kDa type I transmembrane glycoprotein whose variability in molecular weight is dependent upon the nature of the extracellular O-glycans. It is the major sialoglycoprotein on thymocytes, T cells, and neutrophils. It is also present on activated B cells, plasma cells, NK cells, granulocytes, monocytes, macrophages, platelets, and bone marrow hematopoietic stem cells. CD43, which binds to ICAM-1 (CD54), appears to function as an anti-adhesion molecule, inhibiting T cell interactions including T cell killing, and by increasing the threshold for T cell activation.
NCBI Gene ID
6693
Swiss Prot
P16150
Accession Number
P16150
Host
Mouse
Reactivity
Human
Immunogen
KG-1 cells
Clonality
Monoclonal
Clone
[DF-T1]
Conjugation
Biotin
Type
Primary Antibodies
Field of Research
Immunology
Concentration
Batch dependent
Buffer
Supplied in PBS/NaN3
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store vial at 2-8˚ C
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=99-525
Fragment
IgG1
Specificity
CD43
Applications Notes
CD43 Antibody [DF-T1] for use in flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, and immunoprecipitation assays.
Symbol
SPN
NCBI Official Name
Sialophorin
NCBI Organism
Homo sapiens
Other Product Names
GpL115, leukocyte sialoglycoprotein
Tested Applications
ELISA, IHC-Fr, Flow, IP
Physical Properties
Liquid
Curated Selection
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