CD35 Antibody [E11] (FITC)
Product Specifications
Background
The CD35 antigen is composed of four different allotypes having different molecular weights [A (or F) - 160 kDa, B (or S) - 190 kDa, C - 220 kDa, and D - 250 kDa]. It is the receptor for C3b and is found on B cells, a subset of T cells, monocytes, neutrophils, follicular dendritic cells, erythrocytes, and kidney glomelular podocytes. CD35 mediates neutrophil and monocyte phagocytosis of particles coated with C3b and/or C4b. This interaction also enhances phagocytosis mediated by the Fc receptors.
NCBI Gene ID
1378
Swiss Prot
P17927
Accession Number
P17927
Host
Mouse
Reactivity
Human, Rhesus Monkey, Cynomolgus Monkey, Chimpanzee, Baboon
Immunogen
Acute monocytic leukemia cells and normal blood monocytes
Clonality
Monoclonal
Clone
[E11]
Conjugation
FITC
Type
Primary Antibodies
Field of Research
Immunology, Stem Cell
Concentration
Batch dependent
Buffer
Supplied in PBS/NaN3
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store vial at 2-8˚ C
Fragment
IgG1
Specificity
CD35
Applications Notes
CD35 Antibody [E11] for use in flow cytometry, immunohistochemistry, and western blotting assays.
Symbol
CR1
NCBI Official Name
Complement component (3b/4b) receptor 1 (Knops blood group)
NCBI Organism
Homo sapiens
Other Product Names
CR1, complement receptor type 1, C3bR, C4bR, immune adherence receptor
Tested Applications
Flow
Physical Properties
Liquid
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