CD33 Antibody [WM53]
Product Specifications
Background
CD33 is a 67 kDa type I transmembrane glycoprotein and a member of the sialoadhesin family of cell surface receptors. It is absent from pluripotent stem cells but appears on myelomonocytic precursors after CD34. It then continues to be expressed on both the myeloid and monocyte lineages. While it has been reported that CD33 can function as a sialic acid-dependent cell adhesion molecule, cells expressing CD33 require desialylation before they can bind cells bearing the appropriate sialoglycoconjugates. This suggests that inhibitory cis interactions may regulate or block any adhesion function.
NCBI Gene ID
945
Swiss Prot
P20138
Accession Number
P20138
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Clone
[WM53]
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Stem Cell
Concentration
0.1 mg/mL
Buffer
Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store vial at 2-8˚ C
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=99-504
Fragment
IgG1
Specificity
CD33
Applications Notes
CD33 Antibody [WM53] for use in flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, immunoprecipitation, and blocking assays.
Symbol
CD33
NCBI Official Name
CD33 molecule
NCBI Organism
Homo sapiens
Other Product Names
Gp67, p67, Siglec-3
Tested Applications
WB, IHC-P, IHC-Fr, Flow, Blocking, IP
Physical Properties
Liquid
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