CD33 Antibody [WM53]

Product Specifications

Background

CD33 is a 67 kDa type I transmembrane glycoprotein and a member of the sialoadhesin family of cell surface receptors. It is absent from pluripotent stem cells but appears on myelomonocytic precursors after CD34. It then continues to be expressed on both the myeloid and monocyte lineages. While it has been reported that CD33 can function as a sialic acid-dependent cell adhesion molecule, cells expressing CD33 require desialylation before they can bind cells bearing the appropriate sialoglycoconjugates. This suggests that inhibitory cis interactions may regulate or block any adhesion function.

NCBI Gene ID

945

Swiss Prot

P20138

Accession Number

P20138

Host

Mouse

Reactivity

Human

Clonality

Monoclonal

Clone

[WM53]

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology, Stem Cell

Concentration

0.1 mg/mL

Buffer

Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store vial at 2-8˚ C

Fragment

IgG1

Specificity

CD33

Applications Notes

CD33 Antibody [WM53] for use in flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, immunoprecipitation, and blocking assays.