CD11b Antibody [ICRF44] (Biotin)
Product Specifications
Background
CD11b is the 165 kDa alphaM chain which combines with the CD18 beta2 integrin subunit to form the Mac-1 heterodimer. It is expressed on activated lymphocytes, monocytes, granulocytes and a subset of NK cells. CD11b functions in cell-cell and cell-substrate interactions and is a ligand for C3bi, CD50 (ICAM-3), CD54 (ICAM-1) and CD102 (ICAM-2) .
NCBI Gene ID
3684
Swiss Prot
P11215
Accession Number
P11215
Host
Mouse
Reactivity
Human, Pig, Rhesus Monkey, Cynomolgus Monkey, Chimpanzee, Baboon
Immunogen
Rheumatoid synovial cells and human monocytes
Clonality
Monoclonal
Clone
[ICRF44]
Conjugation
Biotin
Type
Primary Antibodies
Field of Research
Immunology, Neuroscience, Signal Transduction
Concentration
Batch dependent
Buffer
Supplied in PBS/NaN3
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store vial at 2-8˚ C
Fragment
IgG1
Specificity
CD11b
Applications Notes
CD11b Antibody [ICRF44] for use in flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, and immunoprecipitation assays.
Symbol
ITGAM
NCBI Official Name
Integrin alpha-M
NCBI Organism
Homo sapiens
Other Product Names
Mac-1alpha, Mo-1, CR3, integrin alphaM, C3biR, ITGAM, CR3A, p170
Tested Applications
WB, ICC, Flow, Blocking, IP, Drug Delivery, Separation
Physical Properties
Liquid
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