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CD3 Antibody [UCHT1]

Product Specifications

Background

CD3, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chains ranging from 16-28 kDa and is closely associated with the T cell antigen receptor (TCR) . CD3 is expressed on 70-80% of normal peripheral blood lymphocytes and on 10-20% of thymocytes. It plays a major role in signaling during antigen recognition, leading to T cell activation. The monoclonal antibody UCHT1 reacts with the 20 kDa epsilon chain of the CD3/TCR complex.

NCBI Gene ID

916

Swiss Prot

P07766

Accession Number

P07766

Host

Mouse

Reactivity

Human

Immunogen

Human peripheral blood lymphocytes from a patient with Sézary's syndrome and infant thymocytes

Clonality

Monoclonal

Clone

[UCHT1]

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Immunology, Signal Transduction

Concentration

0.1 mg/mL

Buffer

Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store vial at 2-8˚ C

Fragment

IgG1

Specificity

CD3

Applications Notes

CD3 Antibody [UCHT1] for use in flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, immunoprecipitation, activation, and blocking assays.

Symbol

CD3E

NCBI Official Name

T-cell surface glycoprotein CD3 epsilon chain

NCBI Organism

Homo sapiens

Other Product Names

CD3epsilon, T3E, TCRE, Leu-4, T3

Tested Applications

Flow

Physical Properties

Liquid

Frequently Asked Questions

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