CD3 Antibody [UCHT1]
Product Specifications
Background
CD3, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chains ranging from 16-28 kDa and is closely associated with the T cell antigen receptor (TCR) . CD3 is expressed on 70-80% of normal peripheral blood lymphocytes and on 10-20% of thymocytes. It plays a major role in signaling during antigen recognition, leading to T cell activation. The monoclonal antibody UCHT1 reacts with the 20 kDa epsilon chain of the CD3/TCR complex.
NCBI Gene ID
916
Swiss Prot
P07766
Accession Number
P07766
Host
Mouse
Reactivity
Human
Immunogen
Human peripheral blood lymphocytes from a patient with Sézary's syndrome and infant thymocytes
Clonality
Monoclonal
Clone
[UCHT1]
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Immunology, Signal Transduction
Concentration
0.1 mg/mL
Buffer
Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store vial at 2-8˚ C
Fragment
IgG1
Specificity
CD3
Applications Notes
CD3 Antibody [UCHT1] for use in flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, immunoprecipitation, activation, and blocking assays.
Symbol
CD3E
NCBI Official Name
T-cell surface glycoprotein CD3 epsilon chain
NCBI Organism
Homo sapiens
Other Product Names
CD3epsilon, T3E, TCRE, Leu-4, T3
Tested Applications
Flow
Physical Properties
Liquid
Frequently Asked Questions
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