CD49b Antibody [HAS-4] (PE)
Product Specifications
Background
CD49b, a member of the integrin family of extracellular matrix and cell adhesion molecules, is the integrin alpha2 chain. CD49b associates noncovalently with CD29, the integrin beta1 subunit, to form the heterodimer integrin alpha2beta1 that binds laminin and collagen. It is expressed on B and T lymphocytes, NK cells, monocytes, platelets, fibroblasts, and long-term cultured T cells. CD49b/CD29 mediates the Mg++-dependent adhesion of platelets to collagen. It may also be utilized by fibroblasts for the reorganization of the collagen matrix during wound healing.
NCBI Gene ID
3673
Swiss Prot
P17301
Accession Number
P17301
Host
Mouse
Reactivity
Human
Immunogen
Human keratinocytes
Clonality
Monoclonal
Clone
[HAS-4]
Conjugation
PE
Type
Primary Antibodies
Field of Research
Cancer, Immunology, Obesity, Signal Transduction
Concentration
Batch dependent
Buffer
Supplied in PBS/NaN3 and a stabilizing agent
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store vial at 2-8˚ C
Fragment
IgG2a
Specificity
CD49b
Applications Notes
CD49b Antibody [HAS-4] for use in flow cytometry assays.
Symbol
ITGA2
NCBI Official Name
Integrin alpha-2
NCBI Organism
Homo sapiens
Other Product Names
Integrin alpha2, VLA-2alpha, very late antigen-2
Tested Applications
Flow
Physical Properties
Liquid
Curated Selection
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