CD44 Antibody [F10-44-2] (FITC)
Product Specifications
Background
CD44, also known as phagocytic glycoprotein-1 (Pgp-1), exists as a large number of different isoforms resulting from alternative RNA splicing. The major isoform expressed on lymphocytes, myeloid cells, and erythrocytes is a glycosylated type I transmembrane protein. Other variable isoforms containing glycosaminoglycans have molecular weights ranging from 110 to 250 kDa and are widely expressed on hematopoietic and non-hematopoietic cells. CD44 contributes to the adhesion of leukocytes to endothelial cells, stromal cells, and the extracellular matrix. It also plays a functional role in cell migration, lymphocyte homing, and adhesion during hematopoiesis and lymphocyte activation.
NCBI Gene ID
960
Swiss Prot
P16070
Accession Number
P16070
Host
Mouse
Reactivity
Human, Ma's Night Monkey
Immunogen
Purified human T cells
Clonality
Monoclonal
Clone
[F10-44-2]
Conjugation
FITC
Type
Primary Antibodies
Field of Research
Signal Transduction, Signal Transduction
Concentration
Batch dependent
Buffer
Supplied in PBS/NaN3
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store vial at 2-8˚ C
Fragment
IgG2a
Specificity
CD44
Applications Notes
CD44 Antibody [F10-44-2] for use in flow cytometry, immunohistochemistry / immunocytochemistry, and western blotting assays.
Symbol
CD44
NCBI Official Name
CD44 molecule (Indian blood group)
NCBI Organism
Homo sapiens
Other Product Names
Pgp-1, H-CAM, ECMR-III, HUTCH-1
Tested Applications
Flow, Cytotoxicity Assay
Physical Properties
Liquid
Curated Selection
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