CD44 Antibody [F10-44-2]

Product Specifications

Background

CD44, also known as phagocytic glycoprotein-1 (Pgp-1), exists as a large number of different isoforms resulting from alternative RNA splicing. The major isoform expressed on lymphocytes, myeloid cells, and erythrocytes is a glycosylated type I transmembrane protein. Other variable isoforms containing glycosaminoglycans have molecular weights ranging from 110 to 250 kDa and are widely expressed on hematopoietic and non-hematopoietic cells. CD44 contributes to the adhesion of leukocytes to endothelial cells, stromal cells, and the extracellular matrix. It also plays a functional role in cell migration, lymphocyte homing, and adhesion during hematopoiesis and lymphocyte activation.

NCBI Gene ID

960

Swiss Prot

P16070

Accession Number

P16070

Host

Mouse

Reactivity

Human, Ma's Night Monkey

Immunogen

Purified human T cells

Clonality

Monoclonal

Clone

[F10-44-2]

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction, Signal Transduction

Concentration

0.1 mg/mL

Buffer

Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store vial at 2-8˚ C

Fragment

IgG2a

Specificity

CD44

Applications Notes

CD44 Antibody [F10-44-2] for use in flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, immunoprecipitation, CMCD, cytotoxicity, depletion, adhesion, activation, purification, and blocking assays.