CD1.1 Antibody [CB3] (FITC)
Product Specifications
Background
CD1 molecules, like MHC I and II, play an important role in the immune system by presenting lipid, glycolipid and lipopeptide antigen to T and NKT cells. The chicken CD1 gene is located in the chicken MHC B locus and has an important implication for the primordial MHC gene evolution. Two proteins have been identified - CD1.1 and CD1.2. Analysis of RNA from blood cells showed that both genes are expressed in Bu-1+ cells and CD8alpha+ cells. CD1.2 is expressed in TCRgammadelta cells but is nearly undetectable in TCRalphabeta. The monoclonal antibody CB3 antibody can identify cells of the B cell lineage and recognizes CD1.1 but not CD1.2 on the surface of transfected mammalian cells.
NCBI Gene ID
425801;425802
Host
Mouse
Reactivity
Chicken
Immunogen
Lymphocytes from the bursa of Fabricius of outbred chickens
Clonality
Monoclonal
Clone
[CB3]
Conjugation
FITC
Type
Primary Antibodies
Field of Research
Immunology
Concentration
0.5 mg/mL
Buffer
Supplied in PBS/NaN3
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store vial at 2-8˚ C
Fragment
IgG1
Specificity
CD1.1
Applications Notes
CD1.1 Antibody [CB3] for use in flow cytometry and immunohistochemistry / immunocytochemistry assays.
Symbol
CD1C
NCBI Official Name
CD1c molecule
NCBI Organism
Gallus gallus
Tested Applications
Flow
Physical Properties
Liquid
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