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MHC Class I Antibody [F21-2]

Product Specifications

Background

Like their mammalian counterparts, avian MHC Class I molecules, also known as B-F antigens, consist of a highly polymorphic alpha-chain noncovalently bound to the invariant beta2-microglobulin subunit. MHC Class I molecules are expressed on most nucleated cells where they present endogenously synthesized antigenic peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells. The monoclonal antibody F21-2 also reacts with turkey MHC Class I.

Host

Mouse

Reactivity

Chicken, Turkey

Clonality

Monoclonal

Clone

[F21-2]

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology

Concentration

0.5 mg/mL

Buffer

Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store vial at 2-8˚ C

Fragment

IgG1

Specificity

MHC Class I

Applications Notes

MHC Class I Antibody [F21-2] for use in flow cytometry, immunohistochemistry, electron microscopy, western blotting, immunoprecipitation, purification, and blocking assays.

Other Product Names

B-F

Tested Applications

IHC-Fr, Flow, Complement Mediated Cell Depletion

Physical Properties

Liquid

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