CD107a Antibody [1D4B]
Product Specifications
Background
CD107a, also known as lysosomal-associated membrane protein 1 (LAMP-1), is a heavily glycosylated type I transmembrane protein that constitutes one of the two major sialoglycoproteins on lysosomal membranes that can be used to distinguish lysosomes from other organelles. It is a ligand for galaptin, an S-type lectin present in extracellular matrix, through its recognition of acetyllactosamine oligosaccharide chains and is a ligand for E-selectin-mediated cell adhesion. CD107a is principally expressed in epithelial cells and macrophages in a variety of organs in normal and beige mutant mice. It may function in protecting the inner surface of the lysosomal membrane by forming a barrier to lysosomal hydrolases.
NCBI Gene ID
16783
Swiss Prot
P11438
Accession Number
P11438
Host
Rat
Reactivity
Mouse
Immunogen
Plasma membrane fraction of mouse embryo NIH/3T3 cell line
Clonality
Monoclonal
Clone
[1D4B]
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Innate Immunity
Concentration
0.5 mg/mL
Buffer
Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store vial at 2-8˚ C
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=99-109
Fragment
IgG2a
Specificity
CD107a
Applications Notes
CD107a Antibody [1D4B] for use in flow cytometry, immunohistochemistry / immunocytochemistry, electron microscopy, western blotting, immunoprecipitation, ELISA, and purification assays.
Symbol
Lamp1
NCBI Official Name
Lysosomal-associated membrane protein 1
NCBI Organism
Mus musculus
Other Product Names
LAMP-1, lysosomal-associated membrane protein 1
Tested Applications
IHC-Fr, ICC, Flow, IP, Separation
Physical Properties
Liquid
Curated Selection
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