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CD86 Antibody [2D10] (Biotin)

Product Specifications

Background

CD86 (B7-2) is an 80 kDa type I integral membrane protein and a member of the immunoglobulin superfamily of cell surface receptors. Along with CD80 (B7-1), CD86 participates in T cell costimulation via interaction with CD28 and CD152 (CTLA-4) . It is expressed at very low density in normal tissues but is rapidly upregulated on stimulated B cells, monocytes, and dendritic cells. Since CD86 has rapid kinetics of induction, it is believed to be the major CD28 ligand expressed early in the immune response.

NCBI Gene ID

12524

Swiss Prot

P42082

Accession Number

P42082

Host

Rat

Reactivity

Mouse

Immunogen

Mouse B cell lymphoma cell line 5C2

Clonality

Monoclonal

Clone

[2D10]

Conjugation

Biotin

Type

Primary Antibodies

Field of Research

Innate Immunity

Concentration

0.5 mg/mL

Buffer

Supplied in PBS/NaN3

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store vial at 2-8˚ C

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=99-095

Fragment

IgG2b

Specificity

CD86

Applications Notes

CD86 Antibody [2D10] for use in flow cytometry, immunohistochemistry, immunoprecipitation, ELISA, and separation assays.

Symbol

Cd86

NCBI Official Name

CD86 antigen

NCBI Organism

Mus musculus

Other Product Names

B7-2, B70, Ly-58

Tested Applications

IHC-P, IHC-Fr, ICC, Flow

Physical Properties

Liquid

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