CD86 Antibody [2D10]
Product Specifications
Background
CD86 (B7-2) is an 80 kDa type I integral membrane protein and a member of the immunoglobulin superfamily of cell surface receptors. Along with CD80 (B7-1), CD86 participates in T cell costimulation via interaction with CD28 and CD152 (CTLA-4) . It is expressed at very low density in normal tissues but is rapidly upregulated on stimulated B cells, monocytes, and dendritic cells. Since CD86 has rapid kinetics of induction, it is believed to be the major CD28 ligand expressed early in the immune response.
NCBI Gene ID
12524
Swiss Prot
P42082
Accession Number
P42082
Host
Rat
Reactivity
Mouse
Immunogen
Mouse B cell lymphoma cell line 5C2
Clonality
Monoclonal
Clone
[2D10]
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Innate Immunity
Concentration
0.5 mg/mL
Buffer
Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store vial at 2-8˚ C
Fragment
IgG2b
Specificity
CD86
Applications Notes
CD86 Antibody [2D10] for use in flow cytometry, immunohistochemistry, immunoprecipitation, ELISA, separation, CMCD, and blocking assays.
Symbol
Cd86
NCBI Official Name
CD86 antigen
NCBI Organism
Mus musculus
Other Product Names
B7-2, B70, Ly-58
Tested Applications
Flow
Physical Properties
Liquid
Frequently Asked Questions
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