H-2Dd Antibody [34-5-8S] (FITC)
Product Specifications
Background
The monoclonal antibody 34-5-8S reacts with a conformational epitope on H-2Dd MHC Class I found on the N-terminal domains of alpha1 and alpha2 chains when complexed with beta2-microglobulin. The antibody does not react with H-2Dd alpha chains synthesized in vitro. Weak cross-reactivity with cells from mice of the H-2b, H-2q, and H-2s haplotypes has been observed by flow cytometric analysis. Reactivity with cells from mice of the H-2f, H-2k, H-2p, and H-2r haplotypes has not been observed. 34-5-8S has been reported to block the recognition of H-2Dd by Ly-49A+, Ly-49C+, and Ly-49G2+ natural killer cells.
NCBI Gene ID
14964
Swiss Prot
P01899
Accession Number
P01899
Host
Mouse
Reactivity
Mouse
Immunogen
BDF1 mouse splenocytes
Clonality
Monoclonal
Clone
[34-5-8S]
Conjugation
FITC
Type
Primary Antibodies
Field of Research
Cancer, Obesity, Signal Transduction
Concentration
0.5 mg/mL
Buffer
Supplied in PBS/NaN3
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store vial at 2-8˚ C
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=99-081
Fragment
IgG2a
Specificity
H-2Dd
Applications Notes
H-2Dd Antibody [34-5-8S] for use in flow cytometry and immunocytochemistry assays.
Symbol
H2-D1
NCBI Official Name
Histocompatibility 2, D region locus 1
NCBI Organism
Mus musculus
Other Product Names
MHC Class I
Tested Applications
IHC-Fr, Flow, IP, Depletion
Physical Properties
Liquid
Curated Selection
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