LPAM-1 Antibody [DATK32]
Product Specifications
Background
The lymphocyte Peyer’s patch adhesion molecule (LPAM-1), also known as integrin alpha4beta7, is a member of the integrin family of cell surface receptors. It is expressed primarily on mucosal lymphocytes but is also present on NK cells and eosinophils. The alpha4beta7 heterodimer mediates the binding of lymphocytes to its ligand, mucosal vascular addressin (MAdCAM-1) on the high endothelial venules, thereby directing the homing of lymphocytes into Peyer’s patches and intestinal lamina propria. The monoclonal antibody DATK32 recognizes a conformational epitope on the heterodimer.
NCBI Gene ID
16401;16421
Swiss Prot
Q00651; P26011
Accession Number
Q00651; P26011
Host
Rat
Reactivity
Mouse
Immunogen
AKR/Cum mouse T lymphoma cell line TK-1
Clonality
Monoclonal
Clone
[DATK32]
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Signal Transduction, Stem Cell
Concentration
0.5 mg/mL
Buffer
Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store vial at 2-8˚ C
Fragment
IgG2a
Specificity
LPAM-1
Applications Notes
LPAM-1 Antibody [DATK32] for use in flow cytometry, immunohistochemistry, immunoprecipitation, and blocking assays.
Symbol
Itga4; Itgb7
NCBI Official Name
Integrin alpha 4; integrin beta 7
NCBI Organism
Mus musculus
Other Product Names
Integrin alpha4beta7, lymphocyte Peyer's patch adhesion molecule
Tested Applications
ICC, Flow
Physical Properties
Liquid
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