CD94 Antibody [18d3] (FITC)
Product Specifications
Background
The monoclonal antibody 18d3 reacts with the mouse CD94 receptor subunit, a type II transmembrane glycoprotein. CD94 is expressed on the surface of NK cells, NK T cells, and some memory phenotype CD8+ cells. When CD94 is paired with NKG2A, C, or E subunit, it binds the nonclassical MHC class Ib molecule Qa-1b and results in a CD94high population by flow cytometry. Approximately half of NK cells do not express NKG2A, C or E; these cells express CD94 on the surface in a form that does not bind Qa-1b and is believed to be nonfunctional, producing a CD94low population by flow cytometry. CD94 is thought to play a role in the adhesion and activation of the NK cell lineage.
NCBI Gene ID
16643
Swiss Prot
O54707
Accession Number
O54707
Host
Rat
Reactivity
Mouse
Immunogen
CHO cells transfected with the B6 allele of CD94
Clonality
Monoclonal
Clone
[18d3]
Conjugation
FITC
Type
Primary Antibodies
Field of Research
Immunology
Concentration
0.5 mg/mL
Buffer
Supplied in PBS/NaN3
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store vial at 2-8˚ C
Fragment
IgG2a
Specificity
CD94
Applications Notes
CD94 Antibody [18d3] for use in flow cytometry assays.
Symbol
Klrd1
NCBI Official Name
Killer cell lectin-like receptor, subfamily D, member 1
NCBI Organism
Mus musculus
Other Product Names
Kp43, KLRD1
Tested Applications
IHC-Fr, Flow
Physical Properties
Liquid
Curated Selection
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