NK1.1 Antibody [PK136]
Product Specifications
Background
NK1.1, a member of the NKR-P1 family of cell surface receptors, is a type II integral membrane glycoprotein with a C-type lectin domain. It is expressed as a disulfide-linked homodimer on all NK cells as well as subsets of thymocytes and peripheral T lymphocytes in selected strains of mice (e.g., C57BL/6, NZB, and CE) . NK1.1 mediates cellular activation and differentiation, and is thought to have a particular role in generating Th2 cells. This product does not react with NK cells of BALB/c mice.
NCBI Gene ID
17059
Swiss Prot
P27814
Accession Number
P27814
Host
Mouse
Reactivity
Mouse
Immunogen
CE mouse spleen enriched for NK-1+ cells and bone marrow cells
Clonality
Monoclonal
Clone
[PK136]
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Innate Immunity
Concentration
0.5 mg/mL
Buffer
Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store vial at 2-8˚ C
Fragment
IgG2a
Specificity
NK1.1
Applications Notes
NK1.1 Antibody [PK136] for use in flow cytometry, immunohistochemistry, immunoprecipitation, depletion, CMCD, blocking, and activation assays.
Symbol
Klrb1c
NCBI Official Name
Killer cell lectin-like receptor subfamily B member 1C
NCBI Organism
Mus musculus
Other Product Names
Ly-55, CD161b/CD161c
Tested Applications
IHC-Fr, Flow
Physical Properties
Liquid
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