NKG2-A/C/E Antibody [20d5]
Product Specifications
Background
The monoclonal antibody 20d5 reacts with an epitope common to the NKG2A, NKG2C and NKG2E isoforms of the NKG2 heterodimer, a member of the c-type lectin family of inhibitory receptors. Mouse NKG2 is a natural killer (NK) cell receptor for the non-classical MHC class I molecule Qa-1b. NKG2 is expressed on NK cells, lymphokine-activated killer (LAK) T cells, and some CD8+ memory T cells. Two-color immunofluorescent staining with the 20d5 antibody reveals two distinct NKG2+ phenotypes within the NK1.1+CD3- spleen cell population: NKG2hi (50%) and NKG2low (50%) . With the exception of DBA/2J mice, NKG2 is expressed on NK1.1+ cells from all mouse strains tested (C57BL/6, BALB/c, 129/J, C3H.SW, AKR/J, SJL) .
NCBI Gene ID
16641;16642;58179
Host
Rat
Reactivity
Mouse
Immunogen
CHO cells transfected with B6 allele of NKG2A gene
Clonality
Monoclonal
Clone
[20d5]
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Concentration
0.5 mg/mL
Buffer
Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store vial at 2-8˚ C
Fragment
IgG2a
Specificity
NKG2-A/C/E
Applications Notes
NKG2-A/C/E Antibody [20d5] for use in flow cytometry and blocking assays.
Symbol
Klrc1
NCBI Official Name
Killer cell lectin-like receptor subfamily C, member 1
NCBI Organism
Mus musculus
Other Product Names
NKG2A, NKG2C, NKG2E
Tested Applications
IHC-P, IHC-Fr, Flow
Physical Properties
Liquid
Frequently Asked Questions
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