Ly-49F Antibody [HBF-719] (PE)
Product Specifications
Background
The monoclonal antibody HBF-719 reacts with the B6 allele of Ly49F, a member of the lectin-like homodimeric Ly49 family of cell surface receptors. Mouse Ly49 receptors exhibit allelic specificity for MHC class I Ia molecules and are thought to serve to prevent natural killer (NK) cells from attacking normal cells while allowing them to attack infected or transformed cells in which class I molecules have been downregulated. These inhibitory receptors are also expressed on subpopulations of mouse CD8+ T cells. The HBF-719 antibody stains ~11% of NK1.1+CD3- splenocytes, and 3.5% (2.5 month old) to 10.0% (11 month old) of CD8+ spleen cells from C57BL/6 mice.
NCBI Gene ID
16637
Swiss Prot
Q60653
Accession Number
Q60653
Host
Mouse
Reactivity
Mouse
Immunogen
CHO-K1 cells transfected with B6 allele of Ly49F gene
Clonality
Monoclonal
Clone
[HBF-719]
Conjugation
PE
Type
Primary Antibodies
Field of Research
Immunology
Concentration
0.1 mg/mL
Buffer
Supplied in PBS/NaN3 and a stabilizing agent
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store vial at 2-8˚ C
Fragment
IgG1
Specificity
Ly-49F
Applications Notes
Ly-49F Antibody [HBF-719] for use in flow cytometry assays.
Symbol
Klra6
NCBI Official Name
Killer cell lectin-like receptor, subfamily A, member 6
NCBI Organism
Mus musculus
Other Product Names
Ly-49
Tested Applications
Flow
Physical Properties
Liquid
Curated Selection
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