TCR beta Antibody [H57-597]
Product Specifications
Background
The alphabeta TCR is expressed on T lymphocytes of all mouse strains tested. The H57-597 monoclonal antibody does not react with gammadelta TCR-bearing cells. Plate-bound or soluble H57-597 activates alphabeta TCR-bearing T cells. In vitro and in vivo, H57-597 can induce immature thymocytes to undergo apoptosis. In vivo administration of H57-597 has been shown to deplete alphabeta TCR-bearing cells to near completion and prevent graft rejection.
NCBI Gene ID
21577
Host
Hamster
Reactivity
Mouse
Immunogen
TCR affinity purified from mouse T-cell hybridoma DO-11.10
Clonality
Monoclonal
Clone
[H57-597]
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Concentration
0.5 mg/mL
Buffer
Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store vial at 2-8˚ C
Fragment
IgG
Specificity
TCRbeta
Applications Notes
TCR beta Antibody [H57-597] for use in flow cytometry, immunohistochemistry / immunocytochemistry, immunoprecipitation, stimulaton, separation, and depletion assays.
Symbol
Tcrb
NCBI Official Name
T cell receptor beta chain
NCBI Organism
Mus musculus
Tested Applications
ELISA, WB, WB-NR, IHC-Fr, ICC, Flow, Blocking, IP, Adhesion
Physical Properties
Liquid
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