CD72.1 Antibody [10.1.D2]
Product Specifications
Background
Murine CD72.1 (Lyb-2.1), a type II integral membrane glycoprotein and a member of the C-lectin family of cell surface receptors, is a differentiation antigen of B cells and is found in mouse strains expressing the Lyb-2.1 allotype. CD72.1 is the ligand of CD5 which is distributed on all T cells and a small number of B cells. The 10.1.D2 monoclonal antibody blocks binding of CD5 to CD72 on the B cell surface which leads to inhibition of the positive signal resulting from CD5/CD72 pairing. However, 10.1.D2 can itself trigger a positive signal by binding CD72.
NCBI Gene ID
12517
Swiss Prot
P21855
Accession Number
P21855
Host
Mouse
Reactivity
Mouse
Immunogen
DBA/2 mouse spleen cells
Clonality
Monoclonal
Clone
[10.1.D2]
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Signal Transduction
Concentration
0.5 mg/mL
Buffer
Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store vial at 2-8˚ C
Fragment
IgG2b
Specificity
CD72.1
Applications Notes
CD72.1 Antibody [10.1.D2] for use in flow cytometry, immunoprecipitation, blocking, costimulation, and activation assays.
Symbol
Cd72
NCBI Official Name
CD72 antigen
NCBI Organism
Mus musculus
Other Product Names
Lyb-2.1, CD72a, Lyb-2a
Tested Applications
WB, IHC-Fr, ICC, Flow
Physical Properties
Liquid
Frequently Asked Questions
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