CD49e Antibody [5H10.27]
Product Specifications
Background
The monoclonal antibody 5H10.27 reacts with the alpha5 chain (VLA-5) of the CD49e/CD29 heterodimeric fibronectin receptor. It is expressed on thymocytes, activated T cells, mast cells, and a variety of mouse cell lines. Soluble 5H10.27 antibody inhibits VLA-5-mediated functions in vitro. Immobilized 5H10.27 has also been demonstrated to costimulate the proliferative response of CD8+ T cells to plate-bound anti-CD3 monoclonal antibody.
NCBI Gene ID
16402
Swiss Prot
P11688
Accession Number
P11688
Host
Rat
Reactivity
Mouse
Immunogen
C57BL/6 x A/J F1 mouse mast cell line MC/9
Clonality
Monoclonal
Clone
[5H10.27]
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Concentration
0.5 mg/mL
Buffer
Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store vial at 2-8˚ C
Fragment
IgG2a
Specificity
CD49e
Applications Notes
CD49e Antibody [5H10.27] for use in flow cytometry, immunohistochemistry, costimulation, blocking, and adhesion assays.
Symbol
Itga5
NCBI Official Name
Integrin alpha 5 (fibronectin receptor alpha)
NCBI Organism
Mus musculus
Other Product Names
Integrin alpha5, VLA-5alpha
Tested Applications
Flow
Physical Properties
Liquid
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